Story-wise, genetic modification is usually centred on humans, probably the most subtle and creepy way of messing with mankind. Playing with the fear of the unknown, genetically altered humans are technically a new species, that may not only surpass but actually replace unaltered humans. The level of modification will vary from subtle changes in "look" , to mental enhancements , to more or less atrocious adaptations to extreme environments . Note that changes in Aliens would be difficult to pinpoint, after all they are alien.
Top 20 Genetic Modification Anime to watch
- 1. Neon Genesis Evangelion
- 2. Suisei no Gargantia
- 3. Shinsekai yori
- 4. Akira
- 5. Dragon Ball Kai
- 6. Ginga Kikoutai Majestic Prince
- 7. Dragon Ball Kai (2014)
- 8. Karneval (TV)
- 9. Terra Formars
- 10. Blood-C: The Last Dark
- 11. Sidonia no Kishi
- 12. Neon Genesis Evangelion: Death & Rebirth
- 13. Digimon Savers
- 14. iDOLM@STER Xenoglossia
- 15. Soukou Kihei Votoms: Red Shoulder Document - Yabou no Roots
- 16. Dead Leaves
- 17. Angel Cop
- 18. Terra Formars: Bugs 2-hen
- 19. Armored Trooper Votoms
- 20. Blade
1. Neon Genesis Evangelion

In the year 2015, the world stands on the brink of destruction. Humanity's last hope lies in the hands of Nerv, a special agency under the United Nations, and their Evangelions, giant machines capable of defeating the Angels who herald Earth's ruin. Gendou Ikari, head of the organization, seeks compatible pilots who can synchronize with the Evangelions and realize their true potential. Aiding in this defensive endeavor are talented personnel Misato Katsuragi, Head of Tactical Operations, and Ritsuko Akagi, Chief Scientist.
Face to face with his father for the first time in years, 14-year-old Shinji Ikari's average life is irreversibly changed when he is whisked away into the depths of Nerv, and into a harrowing new destiny—he must become the pilot of Evangelion Unit-01 with the fate of mankind on his shoulders.
Written by Hideaki Anno, Neon Genesis Evangelion is a heroic tale of a young boy who will become a legend. But as this psychological drama unfolds, ancient secrets beneath the big picture begin to bubble to the surface...
Neon Genesis Evangelion is finished and has 26 Episodes. It is also Known as: Shinseiki Evangelion, 新世紀エヴァンゲリオン, Neon Genesis Evangelion
2. Suisei no Gargantia

In the distant future, a majority of humans have left the Earth, and the Galactic Alliance of Humanity is founded to guide exploration and ensure the prosperity of mankind. However, a significant threat arises in the form of strange creatures called Hideauze, resulting in an interstellar war to prevent humanity's extinction. Armed with Chamber, an autonomous robot, 16-year-old lieutenant Ledo of the Galactic Alliance joins the battle against the monsters. In an unfortunate turn of events, Ledo loses control during the battle and is cast out to the far reaches of space, crash-landing on a waterlogged Earth.
On the blue planet, Gargantia—a large fleet of scavenger ships—comes across Chamber and retrieves it from the ocean, thinking they have salvaged something of value. Mistaking their actions for hostility, Ledo sneaks aboard and takes a young messenger girl named Amy hostage, only to realize that the residents of Gargantia are not as dangerous as he had believed. Faced with uncertainty, and unable to communicate with his comrades in space, Ledo attempts to get his bearings and acclimate to a new lifestyle. But his peaceful days are about to be short-lived, as there is more to this ocean-covered planet than meets the eye.
Gargantia on the Verdurous Planet is finished and has 13 Episodes. It is also Known as: 翠星のガルガンティア, Suisei no Galgantia
3. Shinsekai yori

Following a sudden outbreak of psychokinesis in 0.1% of the population, a rapid transformation swept the world. The godlike ability to manipulate matter remotely turned many power wielders to violence, inciting a long period of upheaval. Finally, after a chaotic era shaped by the rise and fall of oppressive regimes, the psychic humans were able to achieve a fragile peace by isolating their society, creating a new world bound by complex rules.
In the town of Kamisu 66, 12-year-old Saki Watanabe has just awakened to her powers and is relieved to rejoin her friends—the mischievous Satoru Asahina, the shy Mamoru Itou, the cheerful Maria Akizuki, and Shun Aonuma, a mysterious boy whom Saki admires—at Sage Academy, a special school for psychics. However, unease looms as Saki begins to question the fate of those unable to awaken to their powers, and the children begin to get involved with secretive matters such as the rumored Tainted Cats said to abduct children.Shinsekai yori tells the unique coming-of-age story of Saki and her friends as they journey to grow into their roles in the supposed utopia. Accepting these roles, however, might not come easy when faced with the dark and shocking truths of society, and the impending havoc born from the new world.
From the New World is finished and has 25 Episodes. It is also Known as: 新世界より, Shin Sekai yori
4. Akira

Japan, 1988. An explosion caused by a young boy with psychic powers tears through the city of Tokyo and ignites the fuse that leads to World War III. In order to prevent any further destruction, he is captured and taken into custody, never to be heard from again. Now, in the year 2019, a restored version of the city known as Neo-Tokyo—an area rife with gang violence and terrorism against the current government—stands in its place. Here, Shoutarou Kaneda leads "the Capsules," a group of misfits known for riding large, custom motorcycles and being in constant conflict with their rivals "the Clowns."
During one of these battles, Shoutarou's best friend Tetsuo Shima is caught up in an accident with an esper who finds himself in the streets of Tokyo after escaping confinement from a government institution. Through this encounter, Tetsuo begins to develop his own mysterious abilities, as the government seeks to quarantine this latest psychic in a desperate attempt to prevent him from unleashing the destructive power that could once again bring the city to its knees.
Akira is a Movie. It is also Known as: AKIRA(アキラ), Akira
5. Dragon Ball Kai

Five years after the events of Dragon Ball, martial arts expert Gokuu is now a grown man married to his wife Chi-Chi, with a four-year old son named Gohan. While attending a reunion on Turtle Island with his old friends Master Roshi, Krillin, Bulma and others, the festivities are interrupted when a humanoid alien named Raditz not only reveals the truth behind Gokuu's past, but kidnaps Gohan as well.
With Raditz displaying power beyond anything Gokuu has seen before, he is forced to team up with his old nemesis, Piccolo, in order to rescue his son. But when Gokuu and Piccolo reveal the secret of the seven mystical wish-granting Dragon Balls to Raditz, he informs the duo that there is more of his race, the Saiyans, and they won’t pass up an opportunity to seize the power of the Dragon Balls for themselves.
These events begin the saga of Dragon Ball Kai, a story that finds Gokuu and his friends and family constantly defending the galaxy from increasingly more powerful threats. Bizarre, comical, heartwarming and threatening characters come together in a series of battles that push the powers and abilities of Gokuu and his friends beyond anything they have ever experienced.
Dragon Ball Z Kai is finished and has 97 Episodes. It is also Known as: ドラゴンボール改, Dragonball Kai, DBK, DB Kai, DBZ Kai
6. Ginga Kikoutai Majestic Prince

In the latter half of 21st century, humans leave the Earth and begin to live in space. In order to adapt to the environment in space and deal with the hostile aliens in Jupiter, genetically engineered children called "Princes" are artificially raised and trained to be pilots of armed robots "AHSMB . This is a story about one of the teenage "Princes," Hitachi O Izuru, who studies in an academic city Grandzehle.
Majestic Prince is finished and has 24 Episodes. It is also Known as: 銀河機攻隊 マジェスティックプリンス, Ginga Kikoutai Majestic Prince
7. Dragon Ball Kai (2014)

Remastered version of the Majin Buu saga that adheres more to the manga's story.
Note: Only 61 episodes were released in Japan. International Broadcast had 69. Episode count on this page Represents International count.
Dragon Ball Z Kai: The Final Chapters is finished and has 69 Episodes. It is also Known as: ドラゴンボール改, Dragonball Kai, DBK, DB Kai, DBZ Kai,, DBZ Kai,
8. Karneval (TV)

While in search of his precious friend, a young boy named Nai falls captive to a beautiful woman, whose looks are matched only by her taste for human flesh. Meanwhile Gareki, a clever thief, is in the midst of robbing her luxurious home. After causing a distraction, Gareki agrees to help Nai escape, but they are discovered upon the woman's return. As she transforms into a ghoulish monster, the boys flee.
On the run, Nai and Gareki are found by "Circus," a government defense agency that deals with criminal activity too difficult for the police to handle and protects civilians from "varuga"—terrible monsters that devour humans for sustenance. In the hope that it will lead Nai to his missing friend, he and Gareki decide to join Circus. On their perilous journey, they face dangerous varuga and begin to uncover the secrets behind a shadowy organization known as Kafka.
Karneval is finished and has 13 Episodes. It is also Known as: カーニヴァル, Karneval (2013)
9. Terra Formars

Akari Hizamaru will do anything for his beloved childhood friend, including participating in an underground cage fight against a wild bear! As ridiculous as it sounds, Akari does not have any other choice. His friend is dying of a mysterious virus, and the fight is the only way he can get the money to pay for the procedure she so desperately needs. At first glance, it seems like Akari has no chance of beating the dangerous animal, but the brawl reveals that he might have some strange abilities of his own.
Unfortunately, he discovers he has been betrayed and his dear friend may be beyond help. In the aftermath, he meets two people who are part of an organization intending to send a manned mission to Mars. Prior expeditions to Mars ended in disaster when the explorers encountered hostile, mutant cockroaches. Now, they plan another mission with the sole purpose of exterminating the giant monsters because they may be connected to the mysterious virus that is plaguing mankind. Why are there giant cockroaches on Mars? And why does Akari have mysterious abilities that make him well-suited to fight these mutants?
Terraformars is finished and has 13 Episodes. It is also Known as: TERRA FORMARS [テラフォーマーズ], Terra Formars
10. Blood-C: The Last Dark

Having escaped the many horrors of her village, Saya Kisaragi vows to hunt down the monster responsible and make him pay with his life. As she tears through flesh and bone for her vendetta, she encounters SIRRUT, a group of ingenious hackers, who enlist Saya to help them defeat a common enemy—someone she knows all too well.
Unfortunately, the path she follows is paved with tragedy, as once again, Saya faces betrayal at the hands of those she has come to trust. With her back against the wall, the fearsome monster slayer must fight with all her strength and skill if she is to overcome this final mission and exact vengeance.
Blood-C: The Last Dark is a Movie. It is also Known as: 劇場版 ブラッドシー ザ ラスト ダーク, Blood-C Movie, Gekijouban Blood-C
11. Sidonia no Kishi

After destroying Earth many years ago, the alien race Gauna has been pursuing the remnants of humanity—which, having narrowly escaped, fled across the galaxy in a number of giant seed ships. In the year 3394, Nagate Tanikaze surfaces from his lifelong seclusion deep beneath the seed ship Sidonia in search of food on the upper levels, only to find himself dragged into events unfolding without his knowledge.
When the Gauna begin their assault on Sidonia, it's up to Tanikaze—with the help of his fellow soldiers and friends Shizuka Hoshijiro, Izana Shinatose, and Yuhata Midorikawa—to defend humanity's last hope for survival, and defeat their alien foes. Sidonia no Kishi follows Tanikaze as he discovers the world that has been above him his entire life, and becomes the hero Sidonia needs.
Knights of Sidonia is finished and has 12 Episodes. It is also Known as: シドニアの騎士, Sidonia no Kishi
12. Neon Genesis Evangelion: Death & Rebirth

In the year 2015, more than a decade has passed since the catastrophic event known as Second Impact befell mankind. During this time of recovery, a select few learned of beings known as the Angels—colossal malevolent entities with the intention of triggering the Third Impact and wiping out the rest of humanity.
Called into the city of Tokyo-3 by his father Gendou Ikari, teenager Shinji is thrust headlong into humanity's struggle. Separated from Gendou since the death of his mother, Shinji presumes that his father wishes to repair their shattered familial bonds; instead, he discovers that he was brought to pilot a giant machine capable of fighting the Angels, Evangelion Unit-01. Forced to battle against wave after wave of mankind's greatest threat, the young boy finds himself caught in the middle of a plan that could affect the future of humanity forever.
Neon Genesis Evangelion: Death & Rebirth is a Movie. It is also Known as: Shinseiki Evangelion Gekijouban: Shi to Shinsei, 新世紀エヴァンゲリオン劇場版 シト新生, Neon Genesis Evangelion - Death and Rebirth
13. Digimon Savers

Masaru, a second year Junior High student and undefeated street-fighter, is about to learn the meaning of the word "teamwork." After Agumon escapes DATS, an organization that deals with Digimon, it winds up in a fight with Masaru. Soon Yoshino and Lalamon come to capture Agumon, and the two fighters escape. After an evil Digimon appears, it's up to Masaru and Agumon to defeat it with their DNA Charge.
Soon, Masaru must join DATS to put an end to the Digimon coming to Earth. With the help of Yoshino, Ikuto, and Touma, the group must stop any evil Digimon that appear, and return them to the Digital World.
But not everything goes as planned...
Digimon Data Squad is finished and has 48 Episodes. It is also Known as: デジモンセイバーズ, Digimon Savers
14. iDOLM@STER Xenoglossia

107 years ago, the Moon was destroyed in a massive cataclysm that shattered Earth's former satellite into 81 quintillion tons of orbital debris. However, thanks to super-science, the Earth itself was saved and today no one really thinks much about that century-past disaster. Which is why when teenage Haruka Amami auditions for something called the Idolmaster Project, she THINKS she's trying out to be a singing idol. Instead, Haruka finds herself at a secret school run by the Mondenkind Agency, living with a group of other girls who have also been selected as candidates to pilot an iDOL - an advanced robot specifically designed to intercept falling chunks of moon rock. Except, the people who run the Mondenkind Agency aren't exactly knights in shining armor. And then there's the question of whether the iDOLs are really JUST robots. Because from almost the first moment, Haruka starts to feel emotions resonating from within the iDOL called Imber.
IDOLM@STER Xenoglossia is finished and has 26 Episodes. It is also Known as: アイドルマスター XENOGLOSSIA(ゼノグラシア), Idol Master Xenoglossia, Idolmaster Xenoglossia
15. Soukou Kihei Votoms: Red Shoulder Document - Yabou no Roots

After armored trooper pilot Chirico Cuvie is given orders to transfer to Planet Odon, he and all of the other new recruits are sent into a simulated battle to test their abilities. However, this 'simulated battle' turns out to be a serious fight to eliminate those without the necessary skills. Chirico survives along with just three others, despite the fact that he fought while injured. It soon becomes apparent that this is not the first time he has survived against incredible odds, a fact that Colonel Peruzen wishes to exploit. But is Chirico truly immortal?
Armored Trooper Votoms: Red Shoulder Document - Roots of Treachery is finished and has 1 Episodes. It is also Known as: 装甲騎兵ボトムズ レッドショルダードキュメント野望のルーツ, Armored Trooper Votoms: Red Shoulder Document - Yabo no Roots, Armored Trooper Votoms: The Red Shoulder Document - Roots of Ambition
16. Dead Leaves

Pandy and Retro awaken naked on Earth with no recollection of their past. They embark on a devastating crime spree in search of food, clothing and transportation, but are captured by authorities and sent to the infamous lunar penitentiary named Dead Leaves. While incarcerated, they quickly discover that Dead Leaves is also a top-secret cloning facility, occupied by villainous guards and deformed genetic experiments. Ultra-manic chaos and hyper-violent bedlam ensue as they organize a prison break with the aid of their fellow mutant inmates.
Dead Leaves is a Movie. It is also Known as: デッド リーブス, Dead Leaves
17. Angel Cop

Sometime in the future, terrorism in Japan has become commonplace, and the police have become almost as brutal as criminals. A member of the Special Security Force known as Angel, is the best of the best, stopping at nothing in her fight for justice.
Things get interesting for Angel and her partner, Raiden, when they begin investigating a series of murders in which the victims were known criminals, killed in very unpleasant ways. This trio of killers known as Hunters, is a group of psychics that have banded together to hunt down the lowest scum in the city and bring them to justice.
After a couple of encounters between the cops and the psychics, two of the psychics begin to think that maybe they're not the good guys after all; but the third prefers killing to morality. Augmented by cybernetics from a mysterious source, this third hunter heads out on a killing spree, with the Special Security Force as the first target.
Even with help from the other two psychics and her newly cyborged partner , Angel is going to have her work cut out trying to find the rogue psychic and the organization behind the Hunters.
Angel Cop is finished and has 6 Episodes. It is also Known as: エンジェルコップ, Angel Cop
18. Terra Formars: Bugs 2-hen

Adaptation of the Bugs 2 arc of the manga.
Terra Formars: Bugs 2-hen is finished and has 2 Episodes. It is also Known as: テラフォーマーズ バグズ2号編, Terra Formars: Bugs2 2599, TERRAFORMARS OVA
19. Armored Trooper Votoms

A century of bloodshed between warring star systems has plunged nearly 200 worlds into the flames of war. Now, an uneasy truce has settled across the Astragius Galaxy...
Chirico Cuvie, a special forces powered-armor pilot is suddenly transferred into a unit engaged in a secret and highly illegal mission to steal military secrets—from their own military! Now he's on the run...from his own army!
Unsure of his loyalties and to cover their own tracks, Chirico is left behind to die in space. Surviving by luck, the renegade is now hunted by both the conspirators and military intelligence.
He is driven by the haunting image of a mysterious and beautiful woman—the objective of their mission, and his sole clue to unraveling their treacherous scheme. But the conspirators will do anything to preserve their mysterious agenda...
Armored Trooper Votoms is finished and has 52 Episodes. It is also Known as: Soukou Kihei Votoms, 装甲騎兵ボトムズ, Soko Kihei Votoms
20. Blade

The story revolves around Blade, a "Daywalker" vampire hunter who was born with vampire and human blood after a vampire attacked his mother. While visiting Japan on a mission, Blade tracks down Deacon Frost, the vampire who killed his mother. Blade confronts "Existence," a mysterious organization composed of vampires modified by Frost.
Blade is finished and has 12 Episodes. It is also Known as: ブレイド, Blade