The enhancement of humans can take various forms: It can be something comparatively non-intrusive as a power-up drug, a form of machine implantation or cyberization , or outright - possibly atrocious - genetic manipulation . Plot-wise enhanced protagonists in anime usually have to pay a price for their enhancements, be it physical or mental.
Top 19 Human Enhancement Manga to read
- 1. Wo Zhen Bushi Xie Shen Zougou
- 2. Geomppallo Level Up
- 3. Lord of the Mysteries
- 4. Made in Abyss
- 5. Ningyou no Kuni
- 6. Lord of the Mysteries
- 7. NOiSE
- 8. The Ghost in the Shell
- 9. Franken Fran
- 10. Ghost in the Shell: Arise - Sleepless Eye
- 11. Ghost in the Shell: Stand Alone Complex - The Laughing Man
- 12. Ghost in the Shell: Stand Alone Complex
- 13. Trash.
- 14. The Ghost in the Shell 1.5
- 15. Ghost in the Shell 2: Man-Machine Interface
- 16. Hakui no Ousama
- 17. Messiah no Tettsui
- 18. Incoming Mr High Energy
- 19. Coppelion
1. Wo Zhen Bushi Xie Shen Zougou

Lin Jie, a transmigrator, is the owner of a bookstore in another world. He’s kind and warm-hearted, often recommending healing books to customers who are going through a tough time. From time to time, he secretly promotes his own work too. Over time, these customers begin to respect him greatly, some even frequently bringing local specialties to repay his favor. They often seek his professional opinion when it comes to selecting books, and share their experiences with this ordinary bookstore owner to people around them. They respectfully and intimately refer to him using names such as the “Demon God’s Lackey” and “Propagator of the Flesh and Blood Gospel”.
Source: MU
I'm Really Not the Evil God's Lackey is currently publishing . It is also Known as: Flame of Countless Adversity
2. Geomppallo Level Up

The protagonist of a story is always decided from the start. No matter how hard the supporting role tries, they’ll just be a supporting role in the end. Then, the moment Leon accepted his fate as a supporting character, everything changed. The holy sword that was supposed to choose the hero of the oracle came to him.
"You’re untalented, poor, and have no connections? Don’t worry! The Holy Sword can solve anything!"
"There was a period of time when I thought like that too."
Leon’s tale as a hero begins now.
Leveling Up With The Sword is currently publishing . It is also Known as: Overpowered Sword
3. Lord of the Mysteries

Waking up to be faced with a string of mysteries, Zhou Mingrui finds himself reincarnated as Klein Moretti in an alternate Victorian era world where he sees a world filled with machinery, cannons, dreadnoughts, airships, difference machines, as well as Potions, Divination, Hexes, Tarot Cards, Sealed Artifacts… The Light continues to shine but mystery has never gone far. Follow Klein as he finds himself entangled with the Churches of the world—both orthodox and unorthodox—while he slowly develops newfound powers thanks to the Beyonder potions.
Lord of the Mysteries is finished and has null Volumes and 65 Chapters.
4. Made in Abyss

The enormous cave system, known as the Abyss, is the only unexplored place in the world. Nobody knows how deep down goes this titanic pit, inhabited by strange and wondrous creatures and full of mysterious ancient relics which purpose in unknown to modern man. Generations of bold adventurers have been drawn by the cryptic depths of the Abyss. In course of time those bold enough to explore the dangerous pit came to be known as "Cave Raiders."
In Oosu, the town at the edge of the Abyss, there lives a little orphan named Rico, who dreams of becoming as great a cave raider as her mother was and solving the great mystery of the pit. One day exploring the murky depths she stumbles upon a little boy, who turns out to be a robot...
Made in Abyss is currently publishing . It is also Known as: メイドインアビス, Made in Abyss
5. Ningyou no Kuni

The 200,000 KM diameter artificial celestial body of APOSIMZ. Most of its volume is its core space, which is covered by a superstructural shell. Fifty centuries ago, the people who lost a war against the core lost their right to reside legitimately in APOSIMZ, and were left behind on the extremely cold surface. They face the spreading Frame disease. And aggressive automatons which appear frequently on the ruins level. Yet even so, somehow people survive.
Aposimz is finished and has 9 Volumes and 54 Chapters. It is also Known as: 人形の国, Country of Dolls
6. Lord of the Mysteries

With the rising tide of steam power and machinery, who can come close to being a Beyonder? Shrouded in the fog of history and darkness, who or what is the lurking evil that murmurs into our ears?
Waking up to be faced with a string of mysteries, Zhou Mingrui finds himself reincarnated as Klein Moretti in an alternate Victorian era world where he sees a world filled with machinery, cannons, dreadnoughts, airships, difference machines, as well as Potions, Divination, Hexes, Tarot Cards, Sealed Artifacts…
The Light continues to shine but mystery has never gone far. Follow Klein as he finds himself entangled with the Churches of the world—both orthodox and unorthodox—while he slowly develops newfound powers thanks to the Beyonder potions.
Like the corresponding tarot card, The Fool, which is numbered 0—a number of unlimited potential—this is the legend of “The Fool”.
Lord of the Mysteries is finished and has 8 Volumes and 1430 Chapters. It is also Known as: LotM, 诡秘之主
7. NOiSE

The Bible has its Genesis.
The Matrix has The Second Renaissance.
BLAME! has NOiSE.
Through the eyes of police force member Susono Musubi, this one-volume prequel gives readers a glimpse of the world before the Netsphere went haywire. Witness the events that threw the technologically advanced society into chaos: the cancerous growth of the Megastructure, the birth of the parasitic lifeforms called Silicon Creatures, and the development of the ruthless killing machines known as the Safeguards.
Also included in the compilation is Tsutomu Nihei's debut work BLAME which served as the prototype of the acclaimed 10-volume series, BLAME!.
NOiSE is finished and has 1 Volumes and 8 Chapters. It is also Known as: NOiSE, NOiSE
8. The Ghost in the Shell

In the near future, technology has firmly taken root into society at large. Cybernetic implants are nothing uncommon and robots roam as plentiful as humans, all connected through their ''ghosts'' to the electronic datastreams of the net. Major Motoko Kusanagi and the Public Security Section 9 find themselves in a constant battle with the newly created wave of technological terrorists and cyber-hackers. But things take a turn once Motoko gets involved in a certain case involving an extremely dangerous ''ghost'' hacker nicknamed the Puppeteer, as she dives deeper and deeper into the limitless reality of the net, to reach her own startling conclusions.
The Ghost in the Shell is finished and has 1 Volumes and 11 Chapters. It is also Known as: Koukaku Kidoutai: The Ghost in the Shell, 攻殻機動隊 THE GHOST IN THE SHELL, The Ghost in the Shell
9. Franken Fran

Fran can make anyone into anything, raise the dead, switch heads and bodies and give you those eyes that you've always wanted. But do you actually want them? Is it a good thing to raise the dead? Do the ends justify the means? And does Fran care?
Franken Fran is finished and has 8 Volumes and 61 Chapters. It is also Known as: フランケン・ふらん, Franken Furan, Phase 20
10. Ghost in the Shell: Arise - Sleepless Eye

Manga adaption of Ghost in the Shell: Arise.
Ghost in the Shell: Arise - Sleepless Eye is finished and has 0 Volumes and 42 Chapters. It is also Known as: Koukaku Kidoutai: Arise - Sleepless Eye, 攻殻機動隊ARISE~眠らない眼の男 Sleepless Eye~, Ghost in the Shell: Arise - Nemuranai Me no Otoko Sleepless Eye, Ghost in the Shell Arise Nemuranai Me no Otoko, Natsu no Owari ni
11. Ghost in the Shell: Stand Alone Complex - The Laughing Man

Led by Daisuke Aramaki and Motoko Kusanagi, Section 9 deals with such crimes over the entire social spectrum, usually with success. However, when faced with a new A-level hacker nicknamed "The Laughing Man," the team is thrown into a dangerous cat and mouse game, following the hacker's trail as it leaves its mark on Japan.
Ghost in the Shell: Stand Alone Complex - The Laughing Man is finished and has 0 Volumes and null Chapters. It is also Known as: Koukaku Kidoutai: Stand Alone Complex - The Laughing Man, 攻殻機動隊 STAND ALONE COMPLEX ~The Laughing Man~, Ghost in the Shell: Stand Alone Complex - The Laughing Man
12. Ghost in the Shell: Stand Alone Complex

In the not-too-distant future of 2032, the frontier dividing humans and machines has been crossed. Crimes comitted by flesh-and-metal cyborgs are investigated by Section 9, an elite counter-terrorist squad run by Chief Aramaki and his cyborg assistant, Major Motoko Kusanagi. Section 9 has faced countless adversaries in the real world and in cyberspace, but none like 'The Awakened.' It is believed that this lethal group of terrorists can take over the minds and bodies of almost anyone. Used as tools to commit crimes against the state, the victims are unaware of who or what is controlling them. When Major Kusanagi captures one of the victims, she hacks into his cyberbrain to learn the ringleader's identity-what she discovers leads her on a journey deep into the heart of cyberspace, a journey that shakes her to the core.
Ghost in the Shell: Stand Alone Complex is finished and has 3 Volumes and 45 Chapters. It is also Known as: Koukaku Kidoutai: Stand Alone Complex, 攻殻機動隊STAND ALONE COMPLEX, White Maze, The Lost Memory, Revenge of the Cold Machines
13. Trash.

The mafia boss of the Iwashi family is a high school girl named Konomi Minoko. But don’t let her appearance fool you; she has done and seen things normal citizens can’t even imagine. Under her control are two assassins who have gained legendary status for their deadliness and ability to get any job done. Ishikawa Rushia, codenamed Baret, uses a modified handgun that uses a custom made hollow point bullet that explodes the target from the inside. Shirato Marin, codenamed Francesca, uses a original weapon that is a mix between a throwing axe and battle axe. Both of them are Minoko’s high school classmates and seem like normal teenagers but are two of the most feared killers in the mob world who handle missions often involving other assassins and underground groups.
Trash. is finished and has 11 Volumes and 88 Chapters. It is also Known as: trash., Trash.
14. The Ghost in the Shell 1.5

Ghost in the Shell 1.5: Human-Error Processor presents the "lost" Ghost in the Shell stories, created by Shirow Masamune after completing work on the original Ghost in the Shell manga and prior to his tour-de-force, Ghost in the Shell 2: Man-Machine Interface, but never collected until now. Focusing on Section 9 agents in their daily battle against technocrime, Human-Error Processor has all the mind-twisting cybermadness you've come to expect from Ghost in the Shell but set in a more police-procedural context with action and suspense galore.
The Ghost in the Shell 1.5 is finished and has 1 Volumes and 7 Chapters. It is also Known as: Koukaku Kidoutai 1.5: Human-Error Processer, 攻殻機動隊1.5 HUMAN-ERROR PROCESSER, Ghost in the Shell 1.5: Human-Error Processor
15. Ghost in the Shell 2: Man-Machine Interface

Taking place a few years after the first Ghost In The Shell manga. The Major has been missing since then and Ghost in the Shell 2 follows the mysterious Motoko Aramaki as she runs an investigation into a incident at an organ factory and it's consequences. she's on the run to clean up the mess and save herself in the process Meanwhile the former members of section 9 investigate Motoko to find out who she really is.
Ghost in the Shell 2: Man-Machine Interface is finished and has 1 Volumes and 11 Chapters. It is also Known as: Koukaku Kidoutai 2: Manmachine Interface, 攻殻機動隊2 MANMACHINE INTERFACE, Dual Device
16. Hakui no Ousama

In a certain town exists a laboratory named "King Lab" that houses genius scientists who have way too much time on their hands. One day, the culprit of a series of murders arrives at the King Lab and a strange dark comedy begins to unfold...
King in a Lab Coat is currently publishing . It is also Known as: 白衣の王様, Hakui no Ou-sama
17. Messiah no Tettsui

2034, a time when the development of AI advanced greatly and the appearance of the humanoid "Totomo" has been widely accepted. Tamotsu, an ordinary office worker, loses both his daughter and has half his body replaced with mechanical parts due to an accident. While trying to live earnestly with his wife, his body begins to malfunction...
Messiah’s Hammer is finished and has 3 Volumes and 28 Chapters. It is also Known as: メシアの鉄鎚, Messiah no Kanazuchi, El martillo de Mesías, 弥赛亚的铁锤, 彌賽亞的鐵錘, Meshia no Tettsui
18. Incoming Mr High Energy

After a catastrophe, the biggest trouble facing humans is energy shortage! A brand new profession was thus born, controlling various elements such as iron, copper, phosphorus, gold, silicon, and carbon, they are the strongest combat power in the world. Restarting a powerful system, the youth began to be accompanied by compulsive tasks again and again! Challenging missions full of danger time and time again, he gradually became stronger, and went further and further on the road to a great demon
Incoming Mr High Energy is currently publishing . It is also Known as: 高能襲来, Kounou Shuurai, 흙수저, 시스템에게 선택받다, High Energy Strikes, Gao Neng Strikes, High-Energy Strikes
19. Coppelion

In 2016 a meltdown of a nuclear power plant creates a big catastrophe in Tokyo. 20 years later, the city has become a ghost town due to the high levels of radiation. From that area a distress signal is received. The Self Defence forces dispatch 3 girls from the special unit Coppelion to search for survivors. But why aren't they wearing any protection against radiation?
Coppelion is finished and has 26 Volumes and 226 Chapters. It is also Known as: COPPELION, Coppelion